Inhibiting autophagy enhances sulforaphane-induced apoptosis via targeting NRF2 in esophageal squamous cell carcinoma

Sulforaphane (SFN), a natural anti-tumor compound from cruciferous vegetables, has been reported to induce protective autophagy to cancer cells, which might impair the anti-tumor efficiency of SFN. However, the accurate function and mechanism of SFN inducing autophagy in cancers are still obscure, e...

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Bibliografiske detaljer
Udgivet i:Acta Pharm Sin B
Main Authors: Lu, Zhaoming, Ren, Yandan, Yang, Li, Jia, Ang, Hu, Yi, Zhao, Yu, Zhao, Wuduo, Yu, Bin, Zhao, Wen, Zhang, Jianying, Hou, Guiqin
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2021
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Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8148075/
https://ncbi.nlm.nih.gov/pubmed/34094831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.apsb.2020.12.009
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