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Rapamycin synergizes with low-dose oxaliplatin in the HCT116 colon cancer cell line by inducing enhanced apoptosis

The present study aimed to examine the combined effects of oxaliplatin (L-OHP) and rapamycin (RAPA) in the HCT116 colon cancer cell line. The growth inhibitory effect was evaluated by MTT assay as a monotherapy or combination therapy. IC(50) values were determined using CalcuSyn 2.0 software. To det...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: LU, XUEYING, WEI, HAIBO, ZHANG, XIAOJIN, ZHENG, WENXIN, CHANG, CHENG, GU, JINYU
Format: Artigo
Sprache:Inglês
Veröffentlicht: D.A. Spandidos 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3406438/
https://ncbi.nlm.nih.gov/pubmed/22848242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2011.299
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