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DZNep inhibits the proliferation of colon cancer HCT116 cells by inducing senescence and apoptosis
EZH2 is over-expressed in human colon cancer and is closely associated with tumor proliferation, metastasis and poor prognosis. Targeting and inhibiting EZH2 may be an effective therapeutic strategy for colon cancer. 3-Deazaneplanocin A (DZNep), as an EZH2 inhibitor, can suppress cancer cell growth....
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| Опубликовано в: : | Acta Pharm Sin B |
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| Главные авторы: | , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Elsevier
2015
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4629229/ https://ncbi.nlm.nih.gov/pubmed/26579445 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.apsb.2015.01.011 |
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