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DZNep inhibits the proliferation of colon cancer HCT116 cells by inducing senescence and apoptosis

EZH2 is over-expressed in human colon cancer and is closely associated with tumor proliferation, metastasis and poor prognosis. Targeting and inhibiting EZH2 may be an effective therapeutic strategy for colon cancer. 3-Deazaneplanocin A (DZNep), as an EZH2 inhibitor, can suppress cancer cell growth....

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Acta Pharm Sin B
Päätekijät: Sha, Mingquan, Mao, Genxiang, Wang, Guofu, Chen, Yufeng, Wu, Xiaojian, Wang, Zhen
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Elsevier 2015
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4629229/
https://ncbi.nlm.nih.gov/pubmed/26579445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.apsb.2015.01.011
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