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Clonal expansion and myeloid leukemia progression modeled by multiplex gene editing of murine hematopoietic progenitor cells

Recent advances in next-generation sequencing have identified novel mutations and revealed complex genetic architectures in human hematological malignancies. Moving forward, new methods to quickly generate animal models that recapitulate the complex genetics of human hematological disorders are need...

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Bibliografske podrobnosti
izdano v:Exp Hematol
Main Authors: Shi, Xiangguo, Kitano, Ayumi, Jiang, Yajian, Luu, Victor, Hoegenauer, Kevin A., Nakada, Daisuke
Format: Artigo
Jezik:Inglês
Izdano: 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6088788/
https://ncbi.nlm.nih.gov/pubmed/29751067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exphem.2018.04.009
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