Natural product derivative Gossypolone inhibits Musashi family of RNA-binding proteins

BACKGROUND: The Musashi (MSI) family of RNA-binding proteins is best known for the role in post-transcriptional regulation of target mRNAs. Elevated MSI1 levels in a variety of human cancer are associated with up-regulation of Notch/Wnt signaling. MSI1 binds to and negatively regulates translation o...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:BMC Cancer
Asıl Yazarlar: Lan, Lan, Liu, Hao, Smith, Amber R., Appelman, Carl, Yu, Jia, Larsen, Sarah, Marquez, Rebecca T., Wu, Xiaoqing, Liu, Frank Y., Gao, Philip, Gowthaman, Ragul, Karanicolas, John, De Guzman, Roberto N., Rogers, Steven, Aubé, Jeffrey, Neufeld, Kristi L., Xu, Liang
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2018
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6086024/
https://ncbi.nlm.nih.gov/pubmed/30097032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-018-4704-z
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller