The prionlike domain of FUS is multiphosphorylated following DNA damage without altering nuclear localization

FUS (fused in sarcoma) is an abundant, predominantly nuclear protein involved in RNA processing. Under various conditions, FUS functionally associates with RNA and other macromolecules to form distinct, reversible phase-separated liquid structures. Persistence of the phase-separated state and increa...

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Udgivet i:Mol Biol Cell
Main Authors: Rhoads, Shannon N., Monahan, Zachary T., Yee, Debra S., Leung, Andrew Y., Newcombe, Cameron G., O’Meally, Robert N., Cole, Robert N., Shewmaker, Frank P.
Format: Artigo
Sprog:Inglês
Udgivet: The American Society for Cell Biology 2018
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6085830/
https://ncbi.nlm.nih.gov/pubmed/29897835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E17-12-0735
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