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The prionlike domain of FUS is multiphosphorylated following DNA damage without altering nuclear localization

FUS (fused in sarcoma) is an abundant, predominantly nuclear protein involved in RNA processing. Under various conditions, FUS functionally associates with RNA and other macromolecules to form distinct, reversible phase-separated liquid structures. Persistence of the phase-separated state and increa...

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Detalles Bibliográficos
Publicado en:Mol Biol Cell
Main Authors: Rhoads, Shannon N., Monahan, Zachary T., Yee, Debra S., Leung, Andrew Y., Newcombe, Cameron G., O’Meally, Robert N., Cole, Robert N., Shewmaker, Frank P.
Formato: Artigo
Idioma:Inglês
Publicado: The American Society for Cell Biology 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6085830/
https://ncbi.nlm.nih.gov/pubmed/29897835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E17-12-0735
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