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The Role of Post-Translational Modifications on Prion-Like Aggregation and Liquid-Phase Separation of FUS
Subcellular mislocalization and aggregation of the human FUS protein occurs in neurons of patients with subtypes of amyotrophic lateral sclerosis and frontotemporal dementia. FUS is one of several RNA-binding proteins that can functionally self-associate into distinct liquid-phase droplet structures...
Gorde:
| Argitaratua izan da: | Int J Mol Sci |
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| Egile Nagusiak: | , , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
MDPI
2018
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5877747/ https://ncbi.nlm.nih.gov/pubmed/29547565 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19030886 |
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