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The Role of Post-Translational Modifications on Prion-Like Aggregation and Liquid-Phase Separation of FUS
Subcellular mislocalization and aggregation of the human FUS protein occurs in neurons of patients with subtypes of amyotrophic lateral sclerosis and frontotemporal dementia. FUS is one of several RNA-binding proteins that can functionally self-associate into distinct liquid-phase droplet structures...
Guardat en:
| Publicat a: | Int J Mol Sci |
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| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
MDPI
2018
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5877747/ https://ncbi.nlm.nih.gov/pubmed/29547565 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19030886 |
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