Homeobox oncogene activation by pan-cancer DNA hypermethylation

BACKGROUND: Cancers have long been recognized to be not only genetically but also epigenetically distinct from their tissues of origin. Although genetic alterations underlying oncogene upregulation have been well studied, to what extent epigenetic mechanisms, such as DNA methylation, can also induce...

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Detalhes bibliográficos
Publicado no:Genome Biol
Main Authors: Su, Jianzhong, Huang, Yung-Hsin, Cui, Xiaodong, Wang, Xinyu, Zhang, Xiaotian, Lei, Yong, Xu, Jianfeng, Lin, Xueqiu, Chen, Kaifu, Lv, Jie, Goodell, Margaret A., Li, Wei
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6085761/
https://ncbi.nlm.nih.gov/pubmed/30097071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-018-1492-3
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