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DNA epigenome editing using CRISPR-Cas SunTag-directed DNMT3A
BACKGROUND: DNA methylation has widespread effects on gene expression during development. However, our ability to assign specific function to regions of DNA methylation is limited by the poor correlation between global patterns of DNA methylation and gene expression. RESULTS: Here, we utilize nuclea...
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| Publicado no: | Genome Biol |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5604343/ https://ncbi.nlm.nih.gov/pubmed/28923089 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-017-1306-z |
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