DNA epigenome editing using CRISPR-Cas SunTag-directed DNMT3A

BACKGROUND: DNA methylation has widespread effects on gene expression during development. However, our ability to assign specific function to regions of DNA methylation is limited by the poor correlation between global patterns of DNA methylation and gene expression. RESULTS: Here, we utilize nuclea...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Genome Biol
Autors principals: Huang, Yung-Hsin, Su, Jianzhong, Lei, Yong, Brunetti, Lorenzo, Gundry, Michael C., Zhang, Xiaotian, Jeong, Mira, Li, Wei, Goodell, Margaret A.
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2017
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5604343/
https://ncbi.nlm.nih.gov/pubmed/28923089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-017-1306-z
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars