Načítá se...

DNA epigenome editing using CRISPR-Cas SunTag-directed DNMT3A

BACKGROUND: DNA methylation has widespread effects on gene expression during development. However, our ability to assign specific function to regions of DNA methylation is limited by the poor correlation between global patterns of DNA methylation and gene expression. RESULTS: Here, we utilize nuclea...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Genome Biol
Hlavní autoři: Huang, Yung-Hsin, Su, Jianzhong, Lei, Yong, Brunetti, Lorenzo, Gundry, Michael C., Zhang, Xiaotian, Jeong, Mira, Li, Wei, Goodell, Margaret A.
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5604343/
https://ncbi.nlm.nih.gov/pubmed/28923089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-017-1306-z
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!