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Site-specific manipulation of Arabidopsis loci using CRISPR-Cas9 SunTag systems
Understanding genomic functions requires site-specific manipulation of loci via efficient protein effector targeting systems. However, few approaches for targeted manipulation of the epigenome are available in plants. Here, we adapt the dCas9-SunTag system to engineer targeted gene activation and DN...
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| Publicado no: | Nat Commun |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6374409/ https://ncbi.nlm.nih.gov/pubmed/30760722 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-08736-7 |
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