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Synergistic Upregulation of Target Genes by TET1 and VP64 in the dCas9–SunTag Platform

Overexpression of a gene of interest is a general approach used in both basic research and therapeutic applications. However, the conventional approach involving overexpression of exogenous genes has difficulty achieving complete genome coverage, and is also limited by the cloning capacity of viral...

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Pubblicato in:Int J Mol Sci
Autori principali: Morita, Sumiyo, Horii, Takuro, Kimura, Mika, Hatada, Izuho
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7084704/
https://ncbi.nlm.nih.gov/pubmed/32106616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21051574
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