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IL-1β-converting enzyme (caspase-1) in intestinal inflammation

IL-1β-converting enzyme (ICE; caspase-1) is the intracellular protease that cleaves the precursors of IL-1β and IL-18 into active cytokines. In the present study, the effect of ICE deficiency was evaluated during experimental colitis in mice. In acute dextran sulfate sodium-induced colitis, ICE-defi...

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Bibliografiske detaljer
Main Authors: Siegmund, Britta, Lehr, Hans-Anton, Fantuzzi, Giamila, Dinarello, Charles A.
Format: Artigo
Sprog:Inglês
Udgivet: The National Academy of Sciences 2001
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC60856/
https://ncbi.nlm.nih.gov/pubmed/11606779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.231473998
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