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The C3a receptor, caspase-1, and release of IL-1β
In this issue of Blood, Asgari et al report that engagement of the C3a receptor triggers interleukin-1β (IL-1β) processing and release via caspase-1 activation. The role of complement activation in IL-1 production has a long history; complement products function as “alarmins” during innate responses...
Bewaard in:
| Hoofdauteur: | |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
American Society of Hematology
2013
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3829112/ https://ncbi.nlm.nih.gov/pubmed/24235127 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2013-08-518282 |
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