MRI is a DNA Damage Response Adaptor during Classical Non-Homologous End Joining

The modulator of retrovirus infection (MRI or CYREN) is a 30 kDa protein with a conserved N-terminal Ku-binding motif (KBM) and a C-terminal XLF-like motif (XLM). We show that MRI is intrinsically disordered and interacts with many DNA damage response (DDR) proteins, including the kinases ATM and DN...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:Mol Cell
Main Authors: Hung, Putzer J., Johnson, Britney, Chen, Bo-Ruei, Byrum, Andrea K., Bredemeyer, Andrea L., Yewdell, William T., Johnson, Tanya E., Lee, Brian J., Deivasigamani, Shruthi, Hindi, Issa, Amatya, Parmeshwar, Gross, Michael L., Paull, Tanya T., Pisapia, David J., Chaudhuri, Jayanta, Petrini, John J. H., Mosammaparast, Nima, Amarasinghe, Gaya K., Zha, Shan, Tyler, Jessica K., Sleckman, Barry P.
Format: Artigo
Jezik:Inglês
Izdano: 2018
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6083883/
https://ncbi.nlm.nih.gov/pubmed/30017584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2018.06.018
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki