Improved Lentiviral Gene Delivery to Mouse Liver by Hydrodynamic Vector Injection through Tail Vein

Delivery of genes to mouse liver is routinely accomplished by tail-vein injections of viral vectors or naked plasmid DNA. While viral vectors are typically injected in a low-pressure and -volume fashion, uptake of naked plasmid DNA to hepatocytes is facilitated by high pressure and volumes, also kno...

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Detalhes bibliográficos
Publicado no:Mol Ther Nucleic Acids
Main Authors: Dalsgaard, Trine, Cecchi, Claudia R., Askou, Anne Louise, Bak, Rasmus O., Andersen, Pernille O., Hougaard, David, Jensen, Thomas G., Dagnæs-Hansen, Frederik, Mikkelsen, Jacob Giehm, Corydon, Thomas J., Aagaard, Lars
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Gene & Cell Therapy 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6083003/
https://ncbi.nlm.nih.gov/pubmed/30092403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtn.2018.07.005
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