Multigenic lentiviral vectors for combined and tissue-specific expression of miRNA- and protein-based antiangiogenic factors

Lentivirus-based gene delivery vectors carrying multiple gene cassettes are powerful tools in gene transfer studies and gene therapy, allowing coexpression of multiple therapeutic factors and, if desired, fluorescent reporters. Current strategies to express transgenes and microRNA (miRNA) clusters f...

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Bibliografski detalji
Izdano u:Mol Ther Methods Clin Dev
Glavni autori: Askou, Anne Louise, Aagaard, Lars, Kostic, Corinne, Arsenijevic, Yvan, Hollensen, Anne Kruse, Bek, Toke, Jensen, Thomas Gryesten, Mikkelsen, Jacob Giehm, Corydon, Thomas Juhl
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2015
Teme:
Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4449022/
https://ncbi.nlm.nih.gov/pubmed/26052532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mtm.2014.64
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