Multigenic lentiviral vectors for combined and tissue-specific expression of miRNA- and protein-based antiangiogenic factors

Lentivirus-based gene delivery vectors carrying multiple gene cassettes are powerful tools in gene transfer studies and gene therapy, allowing coexpression of multiple therapeutic factors and, if desired, fluorescent reporters. Current strategies to express transgenes and microRNA (miRNA) clusters f...

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Publicado en:Mol Ther Methods Clin Dev
Autores principales: Askou, Anne Louise, Aagaard, Lars, Kostic, Corinne, Arsenijevic, Yvan, Hollensen, Anne Kruse, Bek, Toke, Jensen, Thomas Gryesten, Mikkelsen, Jacob Giehm, Corydon, Thomas Juhl
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2015
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4449022/
https://ncbi.nlm.nih.gov/pubmed/26052532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mtm.2014.64
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