Robust Lentiviral Gene Delivery But Limited Transduction Capacity of Commonly Used Adeno-Associated Viral Serotypes in Xenotransplanted Human Skin

Skin is an easily accessible organ, and therapeutic gene transfer to skin remains an attractive alternative for the treatment of skin diseases. Although we have previously documented potent lentiviral gene delivery to human skin, vectors based on adeno-associated virus (AAV) rank among the most prom...

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Bibliographic Details
Published in:Hum Gene Ther Methods
Main Authors: Jakobsen, Maria, Askou, Anne Louise, Stenderup, Karin, Rosada, Cecilia, Dagnæs-Hansen, Frederik, Jensen, Thomas G., Corydon, Thomas J., Mikkelsen, Jacob Giehm, Aagaard, Lars
Format: Artigo
Language:Inglês
Published: Mary Ann Liebert, Inc. 2015
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Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4554550/
https://ncbi.nlm.nih.gov/pubmed/26204415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hgtb.2014.135
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