Robust Lentiviral Gene Delivery But Limited Transduction Capacity of Commonly Used Adeno-Associated Viral Serotypes in Xenotransplanted Human Skin

Skin is an easily accessible organ, and therapeutic gene transfer to skin remains an attractive alternative for the treatment of skin diseases. Although we have previously documented potent lentiviral gene delivery to human skin, vectors based on adeno-associated virus (AAV) rank among the most prom...

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Bibliografski detalji
Izdano u:Hum Gene Ther Methods
Glavni autori: Jakobsen, Maria, Askou, Anne Louise, Stenderup, Karin, Rosada, Cecilia, Dagnæs-Hansen, Frederik, Jensen, Thomas G., Corydon, Thomas J., Mikkelsen, Jacob Giehm, Aagaard, Lars
Format: Artigo
Jezik:Inglês
Izdano: Mary Ann Liebert, Inc. 2015
Teme:
Research Articles
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4554550/
https://ncbi.nlm.nih.gov/pubmed/26204415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hgtb.2014.135
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