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Targeted genome editing by lentiviral protein transduction of zinc-finger and TAL-effector nucleases

Future therapeutic use of engineered site-directed nucleases, like zinc-finger nucleases (ZFNs) and transcription activator-like effector nucleases (TALENs), relies on safe and effective means of delivering nucleases to cells. In this study, we adapt lentiviral vectors as carriers of designer nuclea...

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書目詳細資料
Main Authors: Cai, Yujia, Bak, Rasmus O, Mikkelsen, Jacob Giehm
格式: Artigo
語言:Inglês
出版: eLife Sciences Publications, Ltd 2014
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3996624/
https://ncbi.nlm.nih.gov/pubmed/24843011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.01911
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