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Simvastatin inhibits smoke-induced airway epithelial injury: implications for COPD therapy

Chronic obstructive pulmonary disease (COPD) is the third leading cause of death. The statin drugs may have therapeutic potential in respiratory diseases such as COPD, but whether they prevent bronchial epithelial injury is unknown. We hypothesised that simvastatin attenuates acute tobacco smoke-ind...

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Détails bibliographiques
Publié dans:Eur Respir J
Auteurs principaux: Davis, Benjamin B., Zeki, Amir A., Bratt, Jennifer M., Wang, Lei, Filosto, Simone, Walby, William F., Kenyon, Nicholas J., Goldkorn, Tzipora, Schelegle, Edward S., Pinkerton, Kent E.
Format: Artigo
Langue:Inglês
Publié: 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6082623/
https://ncbi.nlm.nih.gov/pubmed/23180589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1183/09031936.00042512
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