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Simvastatin inhibits smoke-induced airway epithelial injury: implications for COPD therapy

Chronic obstructive pulmonary disease (COPD) is the third leading cause of death. The statin drugs may have therapeutic potential in respiratory diseases such as COPD, but whether they prevent bronchial epithelial injury is unknown. We hypothesised that simvastatin attenuates acute tobacco smoke-ind...

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Detalhes bibliográficos
Publicado no:Eur Respir J
Main Authors: Davis, Benjamin B., Zeki, Amir A., Bratt, Jennifer M., Wang, Lei, Filosto, Simone, Walby, William F., Kenyon, Nicholas J., Goldkorn, Tzipora, Schelegle, Edward S., Pinkerton, Kent E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6082623/
https://ncbi.nlm.nih.gov/pubmed/23180589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1183/09031936.00042512
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