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Measuring APC/C dependent ubiquitylation in vitro

The anaphase promoting complex/cyclosome (APC/C) is a 1.2 MDa ubiquitin ligase complex with important functions in both proliferating and post-mitotic differentiated cells. In proliferating cells, APC/C controls cell cycle progression by targeting inhibitors of chromosome segregation and mitotic exi...

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Detalhes bibliográficos
Publicado no:Methods Mol Biol
Main Authors: Jarvis, Marc A., Brown, Nicholas G., Watson, Edmond R., VanderLinden, Ryan, Schulman, Brenda A., Peters, Jan-Michael
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6080693/
https://ncbi.nlm.nih.gov/pubmed/26254932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-4939-2957-3_18
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