EM Structure of human APC/C(CDH1)-EMI1 reveals multimodal mechanism of E3 ligase shutdown

Por Frye, Jeremiah J., Brown, Nicholas G., Petzold, Georg, Watson, Edmond R., Grace, Christy R. R., Nourse, Amanda, Jarvis, Marc A., Kriwacki, Richard W., Peters, Jan-Michael, Stark, Holger, Schulman, Brenda A.
Publicado em 2013

APC15 mediates CDC20 auto-ubiquitylation by APC/C(MCC) and MCC disassembly

Por Uzunova, Kristina, Dye, Billy T., Schutz, Hannelore, Ladurner, Rene, Petzold, Georg, Toyoda, Yusuke, Jarvis, Marc A., Brown, Nicholas G., Poser, Ina, Novatchkova, Maria, Mechtler, Karl, Hyman, Anthony A., Stark, Holger, Schulman, Brenda A., Peters, Jan-Michael
Publicado em 2012

Mechanism of APC/C(CDC20) activation by mitotic phosphorylation

Por Qiao, Renping, Weissmann, Florian, Yamaguchi, Masaya, Brown, Nicholas G., VanderLinden, Ryan, Imre, Richard, Jarvis, Marc A., Brunner, Michael R., Davidson, Iain F., Litos, Gabriele, Haselbach, David, Mechtler, Karl, Stark, Holger, Schulman, Brenda A., Peters, Jan-Michael
Publicado no Proc Natl Acad Sci U S A (2016)

Mechanism of polyubiquitination by human Anaphase Promoting Complex: RING repurposing for ubiquitin chain assembly

Por Brown, Nicholas G., Watson, Edmond R., Weissmann, Florian, Jarvis, Marc A., VanderLinden, Ryan, Grace, Christy R. R., Frye, Jeremiah J., Qiao, Renping, Dube, Prakash, Petzold, Georg, Cho, Shein Ei, Alsharif, Omar, Bao, Ju, Davidson, Iain F., Zheng, Jie, Nourse, Amanda, Kurinov, Igor, Peters, Jan-Michael, Stark, Holger, Schulman, Brenda A.
Publicado no Mol Cell (2014)

Dual RING E3 Architectures Regulate Multiubiquitination and Ubiquitin Chain Elongation by APC/C

Por Brown, Nicholas G., VanderLinden, Ryan, Watson, Edmond R., Weissmann, Florian, Ordureau, Alban, Wu, Kuen-Phon, Zhang, Wei, Yu, Shanshan, Mercredi, Peter Y., Harrison, Joseph S., Davidson, Iain F., Qiao, Renping, Lu, Ying, Dube, Prakash, Brunner, Michael R., Grace, Christy R.R., Miller, Darcie J., Haselbach, David, Jarvis, Marc A., Yamaguchi, Masaya, Yanishevski, David, Petzold, Georg, Sidhu, Sachdev S., Kuhlman, Brian, Kirschner, Marc W., Harper, J. Wade, Peters, Jan-Michael, Stark, Holger, Schulman, Brenda A.
Publicado no Cell (2016)