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Endorepellin remodels the endothelial transcriptome toward a pro-autophagic and pro-mitophagic gene signature
Regulation of autophagy by proteolytically cleaved fragments of heparan sulfate proteoglycans is a novel and current research focus in tumor biology. Endorepellin is the C-terminal angiostatic fragment of the heparan sulfate proteoglycan perlecan and induces autophagy in endothelial cells. To furthe...
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| Publié dans: | J Biol Chem |
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| Auteurs principaux: | , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society for Biochemistry and Molecular Biology
2018
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6078466/ https://ncbi.nlm.nih.gov/pubmed/29921586 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.002934 |
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