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Endorepellin-evoked Autophagy Contributes to Angiostasis

Endorepellin, the C-terminal domain of perlecan, is an angiostatic molecule that acts as a potent inducer of autophagy via its interaction with VEGFR2. In this study, we examined the effect of endorepellin on endothelial cells using atomic force microscopy. Soluble endorepellin caused morphological...

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Bibliografische gegevens
Gepubliceerd in:J Biol Chem
Hoofdauteurs: Goyal, Atul, Gubbiotti, Maria A., Chery, Daphney R., Han, Lin, Iozzo, Renato V.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Biochemistry and Molecular Biology 2016
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5016664/
https://ncbi.nlm.nih.gov/pubmed/27435676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.740266
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