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Manganese superoxide dismutase deficiency exacerbates the mitochondrial ROS production and oxidative damage in Chagas disease

In this study, we have investigated the effects of manganese superoxide dismutase (SOD2 or MnSOD) deficiency on mitochondrial function and oxidative stress during Chagas disease. For this, C57BL/6 wild type (WT) and MnSOD(+/-) mice were infected with Trypanosoma cruzi (Tc), and evaluated at 150 days...

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書誌詳細
出版年:PLoS Negl Trop Dis
主要な著者: Wen, Jake J., Garg, Nisha Jain
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2018
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オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6078326/
https://ncbi.nlm.nih.gov/pubmed/30044789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0006687
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