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Manganese superoxide dismutase deficiency exacerbates the mitochondrial ROS production and oxidative damage in Chagas disease

In this study, we have investigated the effects of manganese superoxide dismutase (SOD2 or MnSOD) deficiency on mitochondrial function and oxidative stress during Chagas disease. For this, C57BL/6 wild type (WT) and MnSOD(+/-) mice were infected with Trypanosoma cruzi (Tc), and evaluated at 150 days...

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Библиографические подробности
Опубликовано в: :PLoS Negl Trop Dis
Главные авторы: Wen, Jake J., Garg, Nisha Jain
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2018
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6078326/
https://ncbi.nlm.nih.gov/pubmed/30044789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0006687
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