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Manganese superoxide dismutase deficiency exacerbates the mitochondrial ROS production and oxidative damage in Chagas disease

In this study, we have investigated the effects of manganese superoxide dismutase (SOD2 or MnSOD) deficiency on mitochondrial function and oxidative stress during Chagas disease. For this, C57BL/6 wild type (WT) and MnSOD(+/-) mice were infected with Trypanosoma cruzi (Tc), and evaluated at 150 days...

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Detalhes bibliográficos
Publicado no:PLoS Negl Trop Dis
Main Authors: Wen, Jake J., Garg, Nisha Jain
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6078326/
https://ncbi.nlm.nih.gov/pubmed/30044789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0006687
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