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Manganese superoxide dismutase deficiency triggers mitochondrial uncoupling and the Warburg effect
Manganese superoxide dismutase (MnSOD) is a mitochondrially localized primary antioxidant enzyme, known to be essential for the survival of aerobic life and to play important roles in tumorigenesis. Here, we show that MnSOD deficiency in skin tissues of MnSOD-heterozygous knockout (Sod2(+/−)) mice l...
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| Publicado no: | Oncogene |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4859767/ https://ncbi.nlm.nih.gov/pubmed/25362851 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2014.355 |
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