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Manganese superoxide dismutase deficiency triggers mitochondrial uncoupling and the Warburg effect

Manganese superoxide dismutase (MnSOD) is a mitochondrially localized primary antioxidant enzyme, known to be essential for the survival of aerobic life and to play important roles in tumorigenesis. Here, we show that MnSOD deficiency in skin tissues of MnSOD-heterozygous knockout (Sod2(+/−)) mice l...

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書目詳細資料
發表在:Oncogene
Main Authors: Xu, Yong, Miriyala, Sumitra, Fang, Fang, Bakthavatchalu, Vasudevan, Noel, Teresa, Schnell, David, Wang, Chi, St Clair, William H, St Clair, Daret K
格式: Artigo
語言:Inglês
出版: 2014
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4859767/
https://ncbi.nlm.nih.gov/pubmed/25362851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2014.355
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