Manganese superoxide dismutase is a mitochondrial fidelity protein that protects Polγ against UV-induced inactivation

Manganese superoxide dismutase is a nuclear encoded primary antioxidant enzyme localized exclusively in the mitochondrial matrix. Genotoxic agents, such as UV radiation, generates oxidative stress and cause mitochondrial DNA (mtDNA) damage. The mitochondrial DNA polymerase (Polγ), a major constituen...

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Detalhes bibliográficos
Main Authors: Bakthavatchalu, Vasudevan, Dey, Swatee, Xu, Yong, Noel, Teresa, Jungsuwadee, Paiboon, Holley, Aaron K., Dhar, Sanjit K., Batinic-Haberle, Ines, St Clair, Daret K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3237716/
https://ncbi.nlm.nih.gov/pubmed/21909133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2011.407
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