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Manganese superoxide dismutase is a mitochondrial fidelity protein that protects Polγ against UV-induced inactivation
Manganese superoxide dismutase is a nuclear encoded primary antioxidant enzyme localized exclusively in the mitochondrial matrix. Genotoxic agents, such as UV radiation, generates oxidative stress and cause mitochondrial DNA (mtDNA) damage. The mitochondrial DNA polymerase (Polγ), a major constituen...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , , , , , , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2011
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3237716/ https://ncbi.nlm.nih.gov/pubmed/21909133 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2011.407 |
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