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Manganese Superoxide Dismutase Deficiency Exacerbates Ischemic Brain Damage Under Hyperglycemic Conditions by Altering Autophagy

Both preischemic hyperglycemia and suppression of SOD2 activity aggravate ischemic brain damage. This study was undertaken to assess the effect of SOD2 mutation on ischemic brain damage and its relation to the factors involved in autophagy regulation in hyperglycemic wild-type (WT) and heterozygous...

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Detalhes bibliográficos
Main Authors: Mehta, Suresh L., Lin, Yanling, Chen, Wenge, Yu, Fengshan, Cao, Luyi, He, Qingping, Chan, Pak H., Li, P. Andy
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3124221/
https://ncbi.nlm.nih.gov/pubmed/21720543
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