Manganese Superoxide Dismutase Deficiency Exacerbates Ischemic Brain Damage Under Hyperglycemic Conditions by Altering Autophagy

Both preischemic hyperglycemia and suppression of SOD2 activity aggravate ischemic brain damage. This study was undertaken to assess the effect of SOD2 mutation on ischemic brain damage and its relation to the factors involved in autophagy regulation in hyperglycemic wild-type (WT) and heterozygous...

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Main Authors: Mehta, Suresh L., Lin, Yanling, Chen, Wenge, Yu, Fengshan, Cao, Luyi, He, Qingping, Chan, Pak H., Li, P. Andy
Format: Artigo
Sprog:Inglês
Udgivet: 2011
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3124221/
https://ncbi.nlm.nih.gov/pubmed/21720543
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