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Mitochondrial Susceptibility to Oxidative Stress Exacerbates Cerebral Infarction That Follows Permanent Focal Cerebral Ischemia in Mutant Mice with Manganese Superoxide Dismutase Deficiency

Mitochondrial injury has been implicated in ischemic neuronal injury. Mitochondria, producing adenosine triphosphate by virtue of electron flow, have been shown to be both the sites of superoxide anion (O(2)(−)) production and the target of free radical attacks. We evaluated these mechanisms in an i...

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Bibliografiske detaljer
Udgivet i:J Neurosci
Main Authors: Murakami, Kensuke, Kondo, Takeo, Kawase, Makoto, Li, Yibing, Sato, Shuzo, Chen, Sylvia F., Chan, Pak H.
Format: Artigo
Sprog:Inglês
Udgivet: Society for Neuroscience 1998
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6793388/
https://ncbi.nlm.nih.gov/pubmed/9412501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.18-01-00205.1998
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