Manganese Superoxide Dismutase Mediates the Early Release of Mitochondrial Cytochrome C and Subsequent DNA Fragmentation after Permanent Focal Cerebral Ischemia in Mice

Recent studies have shown that release of mitochondrial cytochrome c is a critical step in the apoptosis process. We have reported that cytosolic redistribution of cytochrome c in vivooccurred after transient focal cerebral ischemia (FCI) in rats and preceded the peak of DNA fragmentation. Although...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Fujimura, Miki, Morita-Fujimura, Yuiko, Kawase, Makoto, Copin, Jean-Christophe, Calagui, Bernard, Epstein, Charles J., Chan, Pak H.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 1999
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6782251/
https://ncbi.nlm.nih.gov/pubmed/10212301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.19-09-03414.1999
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