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FGF2 Dual Warhead Conjugate with Monomethyl Auristatin E and α-Amanitin Displays a Cytotoxic Effect towards Cancer Cells Overproducing FGF Receptor 1

In the rapidly developing field of targeted cancer therapy there is growing interest towards therapeutics combining two or more compounds to achieve synergistic action and minimize the chance of cancer resistance to treatment. We developed a fibroblast growth factor 2 (FGF2)-conjugate bearing two cy...

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Библиографические подробности
Опубликовано в: :Int J Mol Sci
Главные авторы: Świderska, Karolina Weronika, Szlachcic, Anna, Opaliński, Łukasz, Zakrzewska, Małgorzata, Otlewski, Jacek
Формат: Artigo
Язык:Inglês
Опубликовано: MDPI 2018
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6073801/
https://ncbi.nlm.nih.gov/pubmed/30029518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19072098
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