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Crosstalk between p38 and Erk 1/2 in Downregulation of FGF1-Induced Signaling

Mitogen-activated protein kinases (MAPK): Erk1 and Erk2 are key players in negative-feedback regulation of fibroblast growth factor (FGF) signaling. Upon activation, Erk1 and Erk2 directly phosphorylate FGF receptor 1 (FGFR1) at a specific serine residue in the C-terminal part of the receptor, subst...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Zakrzewska, Malgorzata, Opalinski, Lukasz, Haugsten, Ellen M., Otlewski, Jacek, Wiedlocha, Antoni
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6514807/
https://ncbi.nlm.nih.gov/pubmed/31013829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20081826
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