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Phosphorylation of Fibroblast Growth Factor (FGF) Receptor 1 at Ser777 by p38 Mitogen-Activated Protein Kinase Regulates Translocation of Exogenous FGF1 to the Cytosol and Nucleus

Exogenous fibroblast growth factor 1 (FGF1) signals through activation of transmembrane FGF receptors (FGFRs) but may also regulate cellular processes after translocation to the cytosol and nucleus of target cells. Translocation of FGF1 occurs across the limiting membrane of intracellular vesicles a...

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Autors principals: Sørensen, Vigdis, Zhen, Yan, Zakrzewska, Malgorzata, Haugsten, Ellen Margrethe, Wälchli, Sébastien, Nilsen, Trine, Olsnes, Sjur, Wiedlocha, Antoni
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2423127/
https://ncbi.nlm.nih.gov/pubmed/18411303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.02117-07
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