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Increased Protein Stability of FGF1 Can Compensate for Its Reduced Affinity for Heparin
Human FGF1 (fibroblast growth factor 1) is a powerful signaling molecule with a short half-life in vivo and a denaturation temperature close to physiological. Binding to heparin increases the stability of FGF1 and is believed to be important in the formation of FGF1·fibroblast growth factor receptor...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2757240/ https://ncbi.nlm.nih.gov/pubmed/19574212 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.001289 |
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