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Vesicle transmembrane potential is required for translocation to the cytosol of externally added FGF-1

Externally added fibroblast growth factor-1 (FGF-1) is capable of crossing cellular membranes to reach the cytosol and the nucleus in a number of cell types. We have monitored the translocation of the growth factor by two methods: phosphorylation of FGF-1, and prenylation of an FGF-1 mutant that con...

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Detalhes bibliográficos
Main Authors: Małecki, Jędrzej, Więdłocha, Antoni, Wesche, Jørgen, Olsnes, Sjur
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC126202/
https://ncbi.nlm.nih.gov/pubmed/12198150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdf472
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