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Vesicle transmembrane potential is required for translocation to the cytosol of externally added FGF-1

Externally added fibroblast growth factor-1 (FGF-1) is capable of crossing cellular membranes to reach the cytosol and the nucleus in a number of cell types. We have monitored the translocation of the growth factor by two methods: phosphorylation of FGF-1, and prenylation of an FGF-1 mutant that con...

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Udgivet i:EMBO J
Principais autores: Małecki, Jędrzej, Więdłocha, Antoni, Wesche, Jørgen, Olsnes, Sjur
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2002
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Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC126202/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12198150/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/cdf472
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