A mutation in a CD44 variant of inflammatory cells enhances the mitogenic interaction of FGF with its receptor

Synovial fluid cells from joints of rheumatoid arthritis (RA) patients express a novel variant of CD44 (designated CD44vRA), encoding an extra trinucleotide (CAG) transcribed from intronic sequences flanking a variant exon. The CD44vRA mutant was detected in 23 out of 30 RA patients. CD44-negative N...

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Main Authors: Nedvetzki, Shlomo, Golan, Itshak, Assayag, Nathalie, Gonen, Erez, Caspi, Dan, Gladnikoff, Micha, Yayon, Avner, Naor, David
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2003
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC152937/
https://ncbi.nlm.nih.gov/pubmed/12697740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200317100
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