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Shear-induced integrin signaling in platelet phosphatidylserine exposure, microvesicle release, and coagulation
It is currently unclear why agonist-stimulated platelets require shear force to efficiently externalize the procoagulant phospholipid phosphatidylserine (PS) and release PS-exposed microvesicles (MVs). We reveal that integrin outside-in signaling is an important mechanism for this requirement. PS ex...
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| 出版年: | Blood |
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| 主要な著者: | , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society of Hematology
2018
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6073322/ https://ncbi.nlm.nih.gov/pubmed/29853537 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2017-05-785253 |
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