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(Indolylalkyl)piperidine carbamates as inhibitors of fatty acid amide hydrolase (FAAH)
A series of phenyl 4-[(indol-1-yl)alkyl]piperidine carbamates was synthesized and tested for inhibition of the endocannabinoid degrading enzyme fatty acid amide hydrolase (FAAH) and for metabolic stability in rat liver S9 fractions and porcine blood plasma. Structure–activity relationship studies re...
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| Veröffentlicht in: | Medchemcomm |
|---|---|
| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Royal Society of Chemistry
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6072049/ https://ncbi.nlm.nih.gov/pubmed/30108777 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c6md00683c |
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