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Aryl N-[ω-(6-Fluoroindol-1-yl)alkyl]carbamates as Inhibitors of Fatty Acid Amide Hydrolase, Monoacylglycerol Lipase, and Butyrylcholinesterase: Structure–Activity Relationships and Hydrolytic Stability

[Image: see text] A series of aryl N-[ω-(6-fluoroindol-1-yl)alkyl]carbamates with alkyl spacers of varying lengths between the indole and the carbamate group and with differently substituted aryl moieties at the carbamate oxygen were synthesized and tested for inhibition of the pharmacologically int...

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Détails bibliographiques
Publié dans:ACS Omega
Auteurs principaux: Rudolph, Stefan, Dahlhaus, Helmut, Hanekamp, Walburga, Albers, Christian, Barth, Maximilian, Michels, Giulia, Friedrich, Denise, Lehr, Matthias
Format: Artigo
Langue:Inglês
Publié: American Chemical Society 2021
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8158844/
https://ncbi.nlm.nih.gov/pubmed/34056494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.1c01699
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