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(Indolylalkyl)piperidine carbamates as inhibitors of fatty acid amide hydrolase (FAAH)

A series of phenyl 4-[(indol-1-yl)alkyl]piperidine carbamates was synthesized and tested for inhibition of the endocannabinoid degrading enzyme fatty acid amide hydrolase (FAAH) and for metabolic stability in rat liver S9 fractions and porcine blood plasma. Structure–activity relationship studies re...

詳細記述

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書誌詳細
出版年:Medchemcomm
主要な著者: Dahlhaus, Helmut, Hanekamp, Walburga, Lehr, Matthias
フォーマット: Artigo
言語:Inglês
出版事項: Royal Society of Chemistry 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6072049/
https://ncbi.nlm.nih.gov/pubmed/30108777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c6md00683c
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