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GDF15 deficiency promotes high fat diet-induced obesity in mice
Pharmacological treatment of recombinant growth differentiation factor 15 (GDF15) proteins reduces body weight in obese rodents and primates. Paradoxically, circulating GDF15 levels are increased in obesity. To investigate the role of endogenous GDF15 in obesity development, we put GDF15 knockout mi...
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| Publicat a: | PLoS One |
|---|---|
| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Public Library of Science
2018
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6072047/ https://ncbi.nlm.nih.gov/pubmed/30070999 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0201584 |
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