Clcn3 deficiency ameliorates high-fat diet-induced obesity and adipose tissue macrophage inflammation in mice

Obesity induces accumulation of adipose tissue macrophages (ATMs) and ATM-driven inflammatory responses that promote the development of glucose and lipid metabolism disorders. ClC-3 chloride channel/antiporter, encoded by the Clcn3, is critical for some basic cellular functions. Our previous work ha...

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Publicado no:Acta Pharmacol Sin
Main Authors: Ma, Ming-ming, Jin, Chen-chen, Huang, Xue-lian, Sun, Lu, Zhou, Hui, Wen, Xue-jun, Huang, Xiong-qing, Du, Jie-yi, Sun, Hong-shuo, Ren, Zhu-xiao, Liu, Jie, Guan, Yong-yuan, Zhao, Xiao-miao, Wang, Guan-lei
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7470880/
https://ncbi.nlm.nih.gov/pubmed/31165783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41401-019-0229-5
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