Macrophage Migration Inhibitory Factor Deficiency Ameliorates High-Fat Diet Induced Insulin Resistance in Mice with Reduced Adipose Inflammation and Hepatic Steatosis

Macrophage infiltration is a critical determinant of high-fat diet induced adipose tissue inflammation and insulin resistance. The precise mechanisms underpinning the initiation of macrophage recruitment and activation are unclear. Macrophage migration inhibitory factor (MIF), a pro-inflammatory cyt...

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Gepubliceerd in:PLoS One
Hoofdauteurs: Finucane, Orla M., Reynolds, Clare M., McGillicuddy, Fiona C., Harford, Karen A., Morrison, Martine, Baugh, John, Roche, Helen M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2014
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4239060/
https://ncbi.nlm.nih.gov/pubmed/25412423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0113369
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