Gdf11 gene transfer prevents high fat diet-induced obesity and improves metabolic homeostasis in obese and STZ-induced diabetic mice

BACKGROUND: The growth differentiation factor 11 (GDF11) was shown to reverse age-related hypertrophy on cardiomyocytes and considered as anti-aging rejuvenation factor. The role of GDF11 in regulating metabolic homeostasis is unclear. In this study, we investigated the functions of GDF11 in regulat...

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Detalhes bibliográficos
Publicado no:J Transl Med
Main Authors: Lu, Bingxin, Zhong, Jianing, Pan, Jianfei, Yuan, Xiaopeng, Ren, Mingzhi, Jiang, Liping, Yang, Yuqing, Zhang, Guisheng, Liu, Dexi, Zhang, Chunbo
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6915940/
https://ncbi.nlm.nih.gov/pubmed/31847906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-019-02166-1
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