Histone deacetylase inhibitor, CG200745 attenuates renal fibrosis in obstructive kidney disease

Tubulointerstitial fibrosis is a common feature of kidney disease. Histone deacetylase (HDAC) inhibitors have been reported to attenuate renal fibrosis progression. Here, we investigated the effect of CG200745, a novel HDAC inhibitor, on renal fibrosis development in a mouse model of unilateral uret...

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Detaylı Bibliyografya
Yayımlandı:Sci Rep
Asıl Yazarlar: Choi, Hong Sang, Song, Ji Hong, Kim, In Jin, Joo, Soo Yeon, Eom, Gwang Hyeon, Kim, Inkyeom, Cha, Hyunju, Cho, Joong Myung, Ma, Seong Kwon, Kim, Soo Wan, Bae, Eun Hui
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2018
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6070546/
https://ncbi.nlm.nih.gov/pubmed/30068917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-30008-5
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